/ INVESTIGAÇÃO / Bioquímica

2019

Produção científica na área de Bioquímica

Title: Gd- and Eu-Loaded Iron Oxide@Silica Core-Shell Nanocomposites as Trimodal Contrast Agents for Magnetic Resonance Imaging and Optical Imaging Author: Pinho, Sonia L. C.; Sereno, José; Abrunhosa, Antero J.; Delville, Marie-Helene; Rocha, João; Carlos, Luis D.; Geraldes, Carlos F. G. C. Source: INORGANIC CHEMISTRY Volume: 58 Issue: 24 Pages: 16618-16628 DOI: 10.1021/acs.inorgchem.9b02655 Published: DEC 16 2019
Title: Metabolic effects of VO(dmpp)(2) - an ex vivo H-1-HRMAS NMR study to unveil its pharmacological properties Author: Metelo, Ana M.; Arias-Ramos, Nuria; Lopez-Larrubia, Pilar; Castro, M. Margarida C. A. Source: NEW JOURNAL OF CHEMISTRY Volume: 43 Issue: 45 Pages: 17841-17849 DOI: 10.1039/c9nj02491c Published: DEC 7 2019
Title: Developmental changes in the endocrine stress response in orangutans (Pongo pygmaeus) Author: Takeshita, Rafaela S. C.; Mendonça, Renata S.; Bercovitch, Fred B.; Huffman, Michael A. Source: JOURNAL OF COMPARATIVE PHYSIOLOGY B-BIOCHEMICAL SYSTEMS AND ENVIRONMENTAL PHYSIOLOGY Volume: 189 Issue: 6 Pages: 659-672 DOI: 10.1007/s00360-019-01235-7 Published: DEC 2019
Title: Moxifloxacin-loaded acrylic intraocular lenses: In vitro and in vivo performance Author: Filipe, Helena P.; Bozukova, Dimitriya; Pimenta, Andreia; Vieira, Ana Paula; Oliveira, Andreia Sofia; Alves, Patricia; Guiomar, A. Jorge et al. Source: JOURNAL OF CATARACT AND REFRACTIVE SURGERY Volume: 45 Issue: 12 Pages: 1808-1817 DOI: 10.1016/j.jcrs.2019.07.016 Published: DEC 2019
Title: Transfer of glucose hydrogens via acetyl-CoA, malonyl-CoA, and NADPH to fatty acids during de novo lipogenesis[S] Author: Belew, Getachew Debas; Silva, João; Rito, João; Tavares, Ludgero; Viegas, Ivan; Teixeira, José; Oliveira, Paulo J.; Macedo, Maria Paula; Jones, John G. Source: JOURNAL OF LIPID RESEARCH Volume: 60 Issue: 12 Pages: 2050-2056 DOI: 10.1194/jlr.RA119000354 Published: DEC 2019
Title: Shedding light into the health-beneficial properties of Corema album-A vibrational spectroscopy study Author: Martin, D.; Marques, J.;Amado, A. M.; Barroca, M. J.; Moreira da Silva, A.; Batista de Carvalho, L. A. E.; Marques, M. P. M. Source: JOURNAL OF RAMAN SPECTROSCOPY Volume: 51 Issue: 2 Pages: 313-322 DOI: 10.1002/jrs.5775 Published: FEB 2020
Title: Human bone probed by neutron diffraction: the burning process Author: Mamede, A. P.; Marques, M. P. M.; Vassalo, A. R.; Cunha, E.; Goncalves, D.; Parker, S. F.; Kockelmann, W.; Batista de Carvalho, L. A. E. Source: RSC ADVANCES Volume: 9 Issue: 63 Pages: 36640-36648 DOI: 10.1039/c9ra07728f Published: NOV 11 2019
Title: Glucosylceramide synthase silencing combined with the receptor tyrosine kinase inhibitor axitinib as a new multimodal strategy for glioblastoma Author: Morais, Catarina M.; Cunha, Pedro P.; Melo, Tânia; Cardoso, Ana M.; Domingues, Pedro; DRosario Domingues, M.; Pedroso de Lima, Maria C.; Jurado, Amália S. Source: HUMAN MOLECULAR GENETICS Volume: 28 Issue: 21 Pages: 3664-3679 DOI: 10.1093/hmg/ddz152 Published: NOV 1 2019
Title: H-1-P-31 HETCOR NMR elucidates the nature of acid sites in zeolite HZSM-5 probed with trimethylphosphine oxide Author: Bornes, Carlos; Sardo, Mariana; Lin, Zhi; Amelse, Jeffrey; Fernandes, Auguste; Ribeiro, Maria Filipa; Geraldes, Carlos; Rocha, João; Mafra, Luis Source: CHEMICAL COMMUNICATIONS Volume: 55 Issue: 84 Pages: 12635-12638 DOI: 10.1039/c9cc06763a Published: OCT 28 2019
Title: Chemical composition and antimicrobial activity of Satureja montana byproducts essential oils Author: Santos, Jessica D. C.; Coelho, Elisabete; Silva, Rita; Passos, Cláudia P.; Teixeira, Pedro; Henriques, Isabel; Coimbra, Manuel A. Source: INDUSTRIAL CROPS AND PRODUCTS Volume: 137 Pages: 541-548 DOI: 10.1016/j.indcrop.2019.05.058 Published: OCT 1 2019
Title: Enhanced ATP release and CD73-mediated adenosine formation sustain adenosine A(2A) receptor over-activation in a rat model of Parkinson's disease Author: Carmo, Marta; Gonçalves, Francisco Q.; Anas, Paula M. C.; Oses, Jean-Pierre; Fernandes, Francisco D.; Duarte, Filipe, V.; Palmeira, Carlos M.; Tomé, Ângelo R. Source: BRITISH JOURNAL OF PHARMACOLOGY Volume: 176 Issue: 18 Pages: 3666-3680 Special Issue: SI DOI: 10.1111/bph.14771 Published: SEP 2019
Title: Chemotherapeutic Targets in Osteosarcoma: Insights from Synchrotron-MicroFTIR and Quasi-Elastic Neutron Scattering Author: Marques, Maria Paula M.; Batista de Carvalho, Ana L. M.; Mamede, Adriana P.; Santos, Inês P.; Sakai, Victoria Garcia et al. Source: JOURNAL OF PHYSICAL CHEMISTRY B Volume: 123 Issue: 32 Pages: 6968-6979 DOI: 10.1021/acs.jpcb.9b05596 Published: AUG 15 2019
Title: The Administration of Chitosan-Tripolyphosphate-DNA Nanoparticles to Express Exogenous SREBP1a Enhances Conversion of Dietary Carbohydrates into Lipids in the Liver of Sparus aurata Author: Silva-Marrero, Jonas I.; Villasante, Juliana ; Rashidpour, Ania; Palma, Mariana; Viegas, Ivan; Jones, John G. et al. BIOMOLECULES Volume: 9 Issue: 8 DOI: 10.3390/biom9080297 Published: AUG 2019
Title: Validation of an LC-MS/MS Method for the Quantification of Caffeine and Theobromine Using Non-Matched Matrix Calibration Curve Author: Mendes, Vera M.; Coelho, Margarida; Tomé, Ângelo R.; Cunha, Rodrigo A.; Manadas, Bruno Source: MOLECULES Volume: 24 Issue: 16 DOI: 10.3390/molecules24162863 Published: AUG 2019
Title: Salivary gland metabolism in an animal model of chronic kidney disease Author: Carvalho, R. A.; Romero, A. C.; Ibuki, F. K.; Nogueira, F. N. Source: ARCHIVES OF ORAL BIOLOGY Volume: 104 Pages: 40-45 DOI: 10.1016/j.archoralbio.2019.05.026 Published: AUG 2019
Title: How Do Nuclei Couple to the Magnetic Moment of a Paramagnetic Center? A New Theory at the Gauntlet of the Experiments Author: Cerofolini, Linda; Silva, José Malanho; Ravera, Enrico; Romanelli, Maurizio; Geraldes, Carlos F. G. C. et al. Source: JOURNAL OF PHYSICAL CHEMISTRY LETTERS Volume: 10 Issue: 13 Pages: 3610-3614 DOI: 10.1021/acs.jpclett.9b01128 Published: JUL 4 2019
Title: Endometrial Cancer Spheres Show Cancer Stem Cells Phenotype and Preference for Oxidative Metabolism Author: Carvalho, Maria João; Laranjo, Mafalda; Abrantes, Ana Margarida; Casalta-Lopes, João; Sarmento-Santos, Daniela; de Carvalho, Rui et al. Source: PATHOLOGY & ONCOLOGY RESEARCH Volume: 25 Issue: 3 Pages: 1163-1174 DOI: 10.1007/s12253-018-0535-0 Published: JUL 2019
Title: Inorganic nitrate prevents the loss of tight junction proteins and modulates inflammatory events induced by broad-spectrum antibiotics: A role for intestinal microbiota? Author: Rocha, Barbara S.; Correia, Mariana G.; Pereira, Anabela; Henriques, Isabel; Da Silva, Gabriela J.; Laranjinha, João Source: NITRIC OXIDE-BIOLOGY AND CHEMISTRY Volume: 88 Pages: 27-34 DOI: 10.1016/j.niox.2019.04.001 Published: JUL 1 2019
Title: Effect of Duration of Exposure to Fluoride and Type of Diet on Lipid Parameters and De Novo Lipogenesis Author: Dionizio, Aline; Barbosa Silva Pereira, Heloisa Aparecida; Araujo, Tamara Teodoro; Sabino-Arias, Isabela Tomazini; Carvalho, Rui Albuquerque et al. Source: BIOLOGICAL TRACE ELEMENT RESEARCH Volume: 190 Issue: 1 Pages: 157-171 DOI: 10.1007/s12011-018-1542-4 Published: JUL 2019
Title: FTIR Spectroscopy and DFT Calculations to Probe the Kinetics of beta-Carotene Thermal Degradation Author: Martin, Daniel; Amado, Ana M.; Gonzalvez, Alicia G.; Marques, M. Paula M.; Batista de Carvalho, Luis A. E.; Gonzalez Urena, Angel Source: JOURNAL OF PHYSICAL CHEMISTRY A Volume: 123 Issue: 25 Pages: 5266-5273 DOI: 10.1021/acs.jpca.9b02327 Published: JUN 27 2019
Title: First analysis of ancient burned human skeletal remains probed by neutron and optical vibrational spectroscopy Author: Festa, G.; Andreani, C.; Baldoni, M.; Cipollari, V.; Martinez-Labarga, C.; Martini, F.; Marques, M. P. M. et al. Source: SCIENCE ADVANCES Volume: 5 Issue: 6 DOI: 10.1126/sciadv.aaw1292 Published: JUN 2019
Title: Early Cardiac Mitochondrial Molecular and Functional Responses to Acute Anthracycline Treatment in Wistar Rats Author: Pereira, Goncalo C.; Pereira, Susana P.; Pereira, Francisco B.; Lourenco, Nuno; Moreno, António J. et al. Source: TOXICOLOGICAL SCIENCES Volume: 169 Issue: 1 Pages: 137-150 DOI: 10.1093/toxsci/kfz026 Published: MAY 2019
Title: Metal centers in biomolecular solid-state NMR Author: Silva, José Malanho; Cerofolini, Linda; Giuntini, Stefano; Geraldes, Carlos F. G. C.; Macedo, Anjos L.; Parigi, Giacomo et al. Source: JOURNAL OF STRUCTURAL BIOLOGY Volume: 206 Issue: 1 Pages: 99-109 DOI: 10.1016/j.jsb.2018.11.013 Published: APR 1 2019
Title: Ruthenium(II) trithiacyclononane complexes of 7,3 ',4 '-trihydroxyflavone, chrysin and tectochrysin: Synthesis, characterisation, and cytotoxic evaluation Author: Marques, Joana; Silva, Artur M. S.; Marques, Maria Paula M.; Braga, Susana S. Source: INORGANICA CHIMICA ACTA Volume: 488 Pages: 71-79 DOI: 10.1016/j.ica.2019.01.003 Published: MAR 24 2019
Title: A biocompatible redox MRI probe based on a Mn(II)/Mn(III) porphyrin Author: Pinto, Sara M. A.; Calvete, Mário J. F.; Ghica, Mariana E.; Soler, Sérgio; Gallardo, Iluminada; Pallier, Agnes; Laranjo, Mariana B.; Cardoso, Ana M. S.; Castro, M. Margarida C. A.; Brett, Christopher M. A. Source: DALTON TRANSACTIONS Volume: 48 Issue: 10 Pages: 3249-3262 DOI: 10.1039/c8dt04775h Published: MAR 14 2019
Title: Anticancer drug impact on DNA - a study by neutron spectroscopy coupled with synchrotron-based FTIR and EXAFS Author: Batista de Carvalho, Ana L. M.; Mamede, Adriana P.; Dopplapudi, Asha; Sakai, Victoria Garcia; Doherty, James; Frogley, Mark; Marques, M. Paula M. et al. Source: PHYSICAL CHEMISTRY CHEMICAL PHYSICS Volume: 21 Issue: 8 Pages: 4162-4175 DOI: 10.1039/c8cp05881d Published: FEB 28 2019
Title: Hydrophilic Quantum Dots Functionalized with Gd(III)-DO3A Monoamide Chelates as Bright and Effective T-1-weighted Bimodal Nanoprobes Author: Pereira, Maria I. A.; Pereira, Goreti; Monteiro, Camila A. P.; Geraldes, Carlos F. G. C.; Cabral Filho, Paulo E.; Cesar, Carlos L.; de Thomaz, Andre A.; Santos, Beate S. et al. Source: SCIENTIFIC REPORTS Volume: 9 DOI: 10.1038/s41598-019-38772-8 Published: FEB 20 2019
Title: Non-crystallographic symmetry in proteins: Jahn-Teller-like and Butterfly-like effects? Author: Silva, Jose Malanho; Giuntini, Stefano; Cerofolini, Linda; Geraldes, Carlos F. G. C.; Macedo, Anjos L.; Ravera, Enrico; Fragai, Marco; Luchinat, Claudio; Calderone, Vito Source: JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY Volume: 24 Issue: 1 Pages: 91-101 DOI: 10.1007/s00775-018-1630-0 Published: FEB 2019
Title: Non-crystallographic symmetry in proteins: Jahn-Teller-like and Butterfly-like effects? Author: Silva, José Malanho; Giuntini, Stefano; Cerofolini, Linda; Geraldes, Carlos F. G. C.; Macedo, Anjos L.; Ravera, Enrico; Fragai, Marco; Luchinat, Claudio; Calderone, Vito Source: JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY Volume: 24 Issue: 1 Page: 91-101 DOI: 10.1007/s00775-018-1630-0 Published: FEB 2019
Title: Impact of Caffeine Consumption on Type 2 Diabetes-Induced Spatial Memory Impairment and Neurochemical Alterations in the Hippocampus Author: Duarte, João M. N.; Skoug, Cecilia; Silva, Henrique B.; Carvalho, Rui A.; Gruetter, Rolf; Cunha, Rodrigo A. Source: FRONTIERS IN NEUROSCIENCE Volume: 12 DOI: 10.3389/fnins.2018.01015 Published: JAN 9 2019
Title: Development of a bioreactor system for cytotoxic evaluation of pharmacological compounds in living cells using NMR spectroscopy Author: Carvalho, Josué; Alves, Sara; Castro, M. Margarida C. A.; Geraldes, Carlos F. G. C.; Queiroz, João A.; Fonseca, Carla P.; Cruz, Carla Source: JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS Volume: 95 Page: 70-78 DOI: 10.1016/j.vascn.2018.11.004 Published: JAN-FEB 2019
Title: Vanadium Compounds as Enzyme Inhibitors with a Focus on Anticancer Effects Author: Crans, Debbie C.; Barkley, Noah E.; Montezinho, Liliana; Margarida Castro, M. Source: METAL-BASED ANTICANCER AGENTS Book Series: RSC Metallobiology Series Volume: 14 Pages: 169-195 Published: 2019
Title: HSP90: A Key Player in Metal-Induced Carcinogenesis? Author: Abreu, P. L. ; Ferreira, L. M. R.; Cunha-Oliveira, T.; Alpoim, M. C.; Urbano, A. M. Source: HEAT SHOCK PROTEIN 90 IN HUMAN DISEASES AND DISORDERS Book Series: Heat Shock Proteins Volume: 19 Pages: 217-247 DOI: 10.1007/978-3-030-23158-3_11 Published: 2019
Title: The Impact of Antioxidants from the Diet on Breast Cancer Cells Monitored by Raman Microspectroscopy Author: Coutinho Medeiros, Paula Sofia; Marques Batista de Carvalho, Ana Lucia; Ruano, Cristina; Carlos Otero, Juan; Matos Marques, Maria Paula Source: LETTERS IN DRUG DESIGN & DISCOVERY Volume: 16 Issue: 2 Pages: 127-137 DOI: 10.2174/1570180815666180502120804 Published: 2019
Title: Bioinspired-Metalloporphyrin Magnetic Nanocomposite as a Reusable Catalyst for Synthesis of Diastereomeric (-)-Isopulegol Epoxide: Anticancer Activity Against Human Osteosarcoma Cells (MG-63) Author: Dias, Lucas D.; Batista de Carvalho, Ana L. M.; Pinto, Sara M. A.; Aquino, Gilberto L. B.; Calvete, Mario J. F.; Marques, M. P. M. et al. Source: MOLECULES Volume: 24 Issue: 1 DOI: 10.3390/molecules24010052 Published: JAN 1 2019
Title: Metabolic dynamics of human Sertoli cells are differentially modulated by physiological and pharmacological concentrations of GLP-1 Author: Martins, Ana D.; Monteiro, Mariana P.; Silva, Branca M.; Barrose, Alberto; Sousa, Mario; Carvalho, Rui A.; Oliveira, Pedro F.; Alves, Marco G. Source: TOXICOLOGY AND APPLIED PHARMACOLOGY Volume: 362 Pages: 1-8 DOI: 10.1016/j.taap.2018.10.009 Published: JAN 1 2019
Title: Development of a bioreactor system for cytotoxic evaluation of pharmacological compounds in living cells using NMR spectroscopy Author: Carvalho, Josue; (Alves, Sara; Castro, M. Margarida C. A.; Geraldes, Carlos F. G. C.; Queiroz, Joao A.; Fonseca, Carla P.; Cruz, Carla Source: JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS Volume: 95 Pages: 70-78 DOI: 10.1016/j.vascn.2018.11.004 Published: JAN-FEB 2019