/ INVESTIGAÇÃO / Biologia Celular e Molecular
2022
Produção científica na área de Biologia Celular e Molecular
| Title: Microscopy-based phenotypic profiling of infection by Staphylococcus aureus clinical isolates reveals intracellular lifestyle as a prevalent feature Author: Rodrigues Lopes, Inês; Maria Alcantara, Laura; Jorge Silva, Ricardo; Josse, Jerome; Pedrero Vega, Elena; Mano, Miguel; Eulalio, Ana Source: NATURE COMMUNICATIONS Volume: 13 Issue: 1 DOI: 10.1038/s41467-022-34790-9 Published: NOV 22 2022 |
| Title: Leucine and Arginine Availability Modulate Mouse Embryonic Stem Cell Proliferation and Metabolism Author: Correia, Bibiana; Sousa, Maria Inês; Branco, Ana Filipa; Rodrigues, Ana Sofia; Ramalho-Santos, João Source: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Volume: 23 Issue: 22 DOI: 10.3390/ijms232214286 Published: NOV 2022 |
| Title: Potent and Specific Activators for Mitochondrial Sirtuins Sirt3 and Sirt5 Author: Suenkel, Benjamin; Valente, Sergio; Zwergel, Clemens; Palmeira, Carlos M. et al. Source: JOURNAL OF MEDICINAL CHEMISTRY Volume: 65 Issue: 20 Page: 14015-14031 DOI: 10.1021/acs.jmedchem.2c01215 Published : OCT 27 2022 |
| Title: DrugTax: package for drug taxonomy identification and explainable feature extraction Author: Preto, A. J.; Correia, Paulo C.; Moreira, Irina S. Source: JOURNAL OF CHEMINFORMATICS Volume: 14 Issue: 1 DOI: 10.1186/s13321-022-00649-w Published: OCT 27 2022 |
| Title: Microglia-dependent remodeling of neuronal circuits Author: Guedes, Joana R.; Ferreira, Pedro A.; Costa, Jessica M.; Cardoso, Ana L.; Peça, João Source: JOURNAL OF NEUROCHEMISTRY Volume: 163 Issue: 2 Page: 74-93 DOI: 10.1111/jnc.15689 Published: OCT 2022 |
| Title: Brain-derived neurotrophic factor-induced regulation of RNA metabolism in neuronal development and synaptic plasticity Author: Costa, Rui O.; Martins, Luis F.; Tahiri, Emanuel; Duarte, Carlos B. Source: WILEY INTERDISCIPLINARY REVIEWS-RNA Volume: 13 Issue: 5 DOI: 10.1002/wrna.1713 Published: SEP 2022 |
| Title: Using machine-learning-driven approaches to boost hot-spot's knowledge Author: Rosario-Ferreira, Nicia; Bonvin, Alexandre M. J. J.; Moreira, Irina S. Source: WILEY INTERDISCIPLINARY REVIEWS-COMPUTATIONAL MOLECULAR SCIENCE Volume: 12 Issue: 5 DOI: 10.1002/wcms.1602 Published: SEP 2022 |
| Title: Genetic spectrum, retinal phenotype, and peripapillary RNFL thickness in RPGR heterozygotes Author: Marques, João Pedro; Pinheiro, Rosa; Carvalho, Ana Luisa; Raimundo, Miguel; Soares, Mario; Melo, Pedro; Murta, Joaquim; Saraiva, Jorge; Silva, Rufino Source: GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY DOI: 10.1007/s00417-022-05809-0 Published: SEP 2022 |
| Title: BDNF upregulates the synaptic expression of NMDA receptors in hippocampal neurons by a mechanism dependent on local translation Author: Duarte, Carlos; De Luca, Pasqualino; Afonso, Pedro; Mele, Miranda Source: JOURNAL OF NEUROCHEMISTRY Volume: 162 Page: 112-112 Supplement: 1 Special Issue: SI Meeting Abstract: WTH 02-03 Published: AUG 2022 |
| Title: The molecular tweezer CLR01 reduces motor impairments and neuropathology in spinocerebellar ataxia type 3 in vivo models Author: Vilasboas-Campos, Daniela; Duarte-Silva, Sara; Monteiro-Fernandes, Daniela; Pereira-Sousa, Joana; Carvalho, Ana Luisa; Teixeira-Castro, Andreia et al. Source: JOURNAL OF NEUROCHEMISTRY Volume: 162 Page: 92-92 Supplement: 1 Special Issue: SI Meeting Abstract: MTU10-11 Published: AUG 2022 |
| Title: Generation and Characterization of Novel iPSC Lines from a Portuguese Family Bearing Heterozygous and Homozygous GRN Mutations Author: Oliveira, Ana Rafaela; Martins, Solange; Cammarata, Giuseppe; Martins, Mariana; Cardoso, Ana Maria; Almeida, Maria Rosario; Macario, Maria do Carmo; Santana, Isabel; Peça, João; Cardoso, Ana Luisa Source: BIOMEDICINES Volume: 10 Issue: 8 DOI: 10.3390/biomedicines10081905 Published: AUG 2022 |
| Title: Attenuation of Autism-like Behaviors by an Anthocyanin-Rich Extract from Portuguese Blueberries via Microbiota-Gut-Brain Axis Modulation in a Valproic Acid Mouse Model Author: Serra, Diana; Henriques, Joana F.; Sousa, Fabio J.; Laranjo, Mariana; Resende, Rosa; Ferreira-Marques, Marisa; de Freitas, Victor; Silva, Gabriela; Peça, João; Dinis, Teresa C. P. Source: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Volume: 23 Issue: 16 DOI: 10.3390/ijms23169259 Published: AUG 2022 |
| Title: Dysregulated endolysosomal trafficking in cells arrested in the G(1) phase of the host cell cycle impairs Salmonella vacuolar replication Author: Lisowski, Clivia; Dias, Jane; Costa, Susana; Silva, Ricardo Jorge; Mano, Miguel; Eulalio, Ana Source: AUTOPHAGY Volume: 18 Issue: 8 Page: 1785-1800 DOI: 10.1080/15548627.2021.1999561 Published: AUG 3 2022 |
| Title: KBG syndrome in the portuguese population: clinical molecular characterization of 41 patients Author: Neves, Mariana Tomasio; Dias, Patricia; Louro, Pedro; Rosas, Catarina; Fernandes, Sofia; Abreu, Maria; Ferreira, Susana; Melo, Mafalda; Carvalho, Ana Luisa et al. Source: MEDICINE Volume: 101 Issue: 30 Meeting Abstract: P31 Published: JUL 29 2022 |
| Title: Efficient spatially targeted gene editing using a near-infrared activatable protein-conjugated nanoparticle for brain applications Author: Rebelo, Catarina; Reis, Tiago; Guedes, Joana; Saraiva, Claudia; Rodrigues, Artur Filipe; Simões, Susana; Bernardino, Liliana; Peça, João; Pinho, Sonia L. C.; Ferreira, Lino Source: NATURE COMMUNICATIONS Volume: 13 Issue: 1 DOI: 10.1038/s41467-022-31791-6 Published: JUL 16 2022 |
| Title: Molecular Mechanisms of Epilepsy: The Role of the Chloride Transporter KCC2 Author: Belperio, Giorgio; Corso, Claudia; Duarte, Carlos B.; Mele, Miranda Source: JOURNAL OF MOLECULAR NEUROSCIENCE Volume: 72 Issue: 7 Page: 1500-1515 Special Issue: SI DOI: 10.1007/s12031-022-02041-7 Published: JUL 2022 |
| Title: Cumulus cells mitochondrial membrane potential as a marker of oocyte competence in assisted reproduction Author: Reis, S.; Almeida-Santos, T.; Ramalho-Santos, J.; Sousa, A. P. Source: HUMAN REPRODUCTION Volume: 37 Page: I313-I314 Supplement: 1 Meeting Abstract: P-259 Published: JUL 2022 |
| Title: Spatiotemporal dynamics of SIRT 1, 2 and 3 during in vitro maturation of bovine oocytes Author: Ferreira, Ana Filipa; Machado-Simões, Juliana; Soares, Maria; Sousa, Ana Paula; Ramalho-Santos, João; Almeida-Santos, Teresa Source: THERIOGENOLOGY Volume: 186 Page: 60-69 DOI: 10.1016/j.theriogenology.2022.04.004 Published: JUL 1 2022 |
| Title: Extracellular Vesicles Secreted by Mononuclear Cells from Mmbilical Cord Blood Induce Neuroprotection and Angiogenesis and Attenuate Microglia Reactivity in a Mouse Model of Brain Ischemia Author: Lino, M.; Rondão, T.; Banerjee, A.; Aires, I.; Rodrigues, M.; Fernandes, D.; Sargento Freitas, J.; Carvalho, A. L.; Pereira, F.; Ferreira, L. Source: EUROPEAN JOURNAL OF CLINICAL INVESTIGATION Volume: 52 Supplement: 1 Special Issue: SI Meeting Abstract: 56ASM-0170 Published: JUN 2022 |
| Title: Proteomic approach to the characterization of unknown origin male infertility Author: Cristo, M. I.; Pacheco, R.; Silva, A. F.; Sousa, A. P.; Moura-Ramos, M.; Almeida-Santos; Ramalho-Santos, J.; Amaral Source: EUROPEAN JOURNAL OF CLINICAL INVESTIGATION Volume: 52 Supplement: 1 Special Issue: SI Published: JUN 2022 |
| Title: It takes two to tango: The involvement of certain environmental endocrine-disrupting chemicals in male infertility aetiology Author: Tavares, R.; Alfaiate, M. I.; Carola, C.; Antonio Santos, R.; Sousa, A. P.; Almeida-Santos, T.; Ramalho-Santos, J. Source: EUROPEAN JOURNAL OF CLINICAL INVESTIGATION Volume: 52 Supplement: 1 Special Issue: SI Meeting Abstract: 56ASM-0267 Published: JUN 2022 |
| Title: Dissection of the role of microRNAs in cardiac fibrosis through functional genomics screenings Author: Rodrigues, F.; Bexiga, M.; Varanda, A.; Mano, M. Source: CARDIOVASCULAR RESEARCH Volume: 118 Issue: SUPPL 1 Supplement: 1 Special Issue: SI DOI: 10.1093/cvr/cvac066.150 Published: JUN 10 2022 |
| Title: Aberrant hippocampal transmission and behavior in mice with a stargazin mutation linked to intellectual disability Author: Caldeira, G. L.; Inacio, A. S.; Beltrao, N.; Barreto, C. A., V; Guedes, J.; Peça, J.; Carvalho, A. L. Source: MOLECULAR PSYCHIATRY Volume: 27 Issue: 5 Page: 2457-2469 DOI: 10.1038/s41380-022-01487-w Published: MAY 2022 |
| Title: Clinical/Demographic Functional Testing and Multimodal Imaging Differences between Genetically Solved and Unsolved Retinitis Pigmentosa Author: Marques, João Pedro; Marta, Ana; Geada, Sara; Carvalho, Ana Luisa; Meneres, Pedro; Murta, Joaquim; Saraiva, Jorge; Silva, Rufino Source: OPHTHALMOLOGICA Volume: 245 Issue: 2 Page: 134-143 DOI: 10.1159/000520305 Published: MAY 2022 |
| Title: Liver Graft Hypothermic Static and Oxygenated Perfusion (HOPE) Strategies: A Mitochondrial Crossroads Author: Bardallo, Raquel G.; da Silva, Rui T.; Carbonell, Teresa; Palmeira, Carlos; Folch-Puy, Emma; Rosello-Catafau, Joan; Adam, Rene; Panisello-Rosello, Arnau Source: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Volume: 23 Issue: 10 DOI: 10.3390/ijms23105742 Published: MAY 2022 |
| Title: The Neural Circuit Architecture of Social Hierarchy in Rodents and Primates Author: Ferreira-Fernandes, Emanuel; Peça, João Source: FRONTIERS IN CELLULAR NEUROSCIENCE Volume: 16 DOI: 10.3389/fncel.2022.874310 Published: MAY 12 2022 |
| Title: Frequency of cystoid macular edema and vitreomacular interface disorders in genetically solved syndromic and non-syndromic retinitis pigmentosa Author: Marques, João Pedro; Neves, Emmanuel; Geada, Sara; Carvalho, Ana Luisa; Murta, Joaquim; Saraiva, Jorge; Silva, Rufino et al. Source: GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY DOI: 10.1007/s00417-022-05649-y Published: APR 2022 |
| Title: EYS-Associated Sector Retinitis Pigmentosa Author: Marques, João Pedro; Porto, Fernanda Belga Ottoni; Carvalho, Ana Luisa; Neves, Emmanuel; Chen, Rui; Sampaio, Shirley Aparecida Madureira; Murta, Joaquim et al. Source: GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY Volume: 260 Issue: 4 Page: 1405-1413 DOI: 10.1007/s00417-021-05411-w Published: APR 2022 |
| Title: Differential Oxygen Exposure Modulates Mesenchymal Stem Cell Metabolism and Proliferation through mTOR Signaling Author: Moniz, Inês; Ramalho-Santos, João; Branco, Ana F. Source: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Volume: 23 Issue: 7 DOI: 10.3390/ijms23073749 Published: APR 2022 |
| Title: Mitochondrial and metabolic dysfunction in ageing and age-related diseases Author: Amorim, João A.; Coppotelli, Giuseppe; Rolo, Anabela P.; Palmeira, Carlos M.; Ross, Jaime M.; Sinclair, David A. Source: NATURE REVIEWS ENDOCRINOLOGY Volume: 18 Issue: 4 Page: 243-258 DOI: 10.1038/s41574-021-00626-7 Published: APR 2022 |
| Title: Mitochondria-Targeted Compounds to Assess and Improve Human Sperm Function Author: Escada-Rebelo, Sara; Cristo, Maria Inês; Ramalho-Santos, João; Amaral, Sandra Source: ANTIOXIDANTS & REDOX SIGNALING DOI: 10.1089/ars.2021.0238 Published: MAR 2022 |
| Title: Mushrooms on the plate: Trends towards NAFLD treatment, health improvement and sustainable diets Author: Fontes, Adriana; Ramalho-Santos, João; Zischka, Hans; Azul, Anabela Marisa Source: EUROPEAN JOURNAL OF CLINICAL INVESTIGATION Volume: 52 Issue: 3 Special Issue: SI DOI: 10.1111/eci.13667 Published: MAR 2022 |
| Title: SARS-CoV-2 Membrane Protein: From Genomic Data to Structural New Insights Author: Marques-Pereira, Catarina; Pires, Manuel N.; Gouveia, Raquel P.; Pereira, Nadia N.; Caniceiro, Ana B.; Rosário-Ferreira, Nicia; Moreira, Irina S. Source: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Volume: 23 Issue: 6 DOI: 10.3390/ijms23062986 Published: MAR 2022 |
| Title: The Use of a Single, Novel Preservation Solution in Split Liver Transplantation and Hypothermic Oxygenated Machine Perfusion Author: Panisello-Rosello, Arnau; da Silva, Rui T.; Folch-Puy, Emma; Carbonell, Teresa; Palmeira, Carlos M. et al. Source: TRANSPLANTATION Volume: 106 Issue: 3 Page: E187-E188 DOI: 10.1097/TP.0000000000003984 Published: MAR 2022 |
| Title: The use of comics to promote health awareness: A template using nonalcoholic fatty liver disease Author: Alemany-Pages, Mireia; Azul, Anabela Marisa; Ramalho-Santos, João Source: EUROPEAN JOURNAL OF CLINICAL INVESTIGATION Volume: 52 Issue: 3 Special Issue: SI DOI: 10.1111/eci.13642 Published: MAR 2022 |
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Title: PEG35 as a Preconditioning Agent against Hypoxia/Reoxygenation Injury Author: Teixeira da Silva, Rui; Machado, Ivo F.; Teodoro, João S.; Panisello-Rosello, Arnau; Rosello-Catafau, Joan; Rolo, Anabela P.; Palmeira, Carlos M. Source: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Volume: 23 Edição: 3 DOI: 10.3390/ijms23031156 Published: FEB 2022 |
| Title: Shaping of Hepatic Ischemia/Reperfusion Events: The Crucial Role of Mitochondria Author: Teodoro, João S.; Da Silva, Rui T.; Machado, Ivo F.; Panisello-Rosello, Arnau; Rosello-Catafau, Joan; Rolo, Anabela P.; Palmeira, Carlos M. Source: CELLS Volume: 11 Issue: 4 DOI: 10.3390/cells11040688 Published: FEB 2022 |
| Title: Posttranslational modifications of proteins are key features in the identification of CSF biomarkers of multiple sclerosis Author: Salazar, Ivan L.; Lourenco, Ana S. T.; Manadas, Bruno; Baldeiras, Inês; Ferreira, Claudia; Teixeira, Anabela Claro; Duarte, Carlos B. et al. Source: JOURNAL OF NEUROINFLAMMATION Volume: 19 Issue: 1 DOI: 10.1186/s12974-022-02404-2 Published: FEB 8 2022 |
| Title: IGL-2 as a Unique Solution for Cold Static Preservation and Machine Perfusion in Liver and Mitochondrial Protection Author: Da Silva, Rui Teixeira; Bardallo, Raquel G.; Folch-Puy, Emma; Carbonell, Teresa; Palmeira, Carlos M. et al. Source: TRANSPLANTATION PROCEEDINGS Volume: 54 Edição: 1 Página: 73-76 DOI: 10.1016/j.transproceed.2021.10.008 Published: JAN-FEB 2022 |
| Title: Network biology and artificial intelligence drive the understanding of the multidrug resistance phenotype in cancer Author: Bueschbell, Beatriz; Caniceiro, Ana Beatriz; Suzano, Pedro M. S.; Machuqueiro, Miguel; Rosario-Ferreira, Nicia; Moreira, Irina S. Source: DRUG RESISTANCE UPDATES Volume: 60 DOI: 10.1016/j.drup.2022.100811 Published: JAN 2022 |
| Title: Class A and C GPCR Dimers in Neurodegenerative Diseases Author: Caniceiro, Ana B. B.; Bueschbell, Beatriz; Schiedel, Anke C. C.; Moreira, Irina S. S. Source: CURRENT NEUROPHARMACOLOGY Volume: 20 Issue: 11 Page: 2081-2141 DOI: 10.2174/1570159X20666220327221830 Published: 2022 |
| Title: From single-omics to interactomics: How can ligand-induced perturbations modulate single-cell phenotypes? Author: Piochi, L. F.; Gaspar, A. T.; Rosario-Ferreira, N.; Preto, A. J.; Moreira, I. S. Edited by: Donev, R Source: PROTEIN INTERACTION NETWORKS, VOL. 131 Book Series Advances in Protein Chemistry and Structural Biology Page: 45-83 DOI: 10.1016/bs.apcsb.2022.05.006 Published: 2022 |
| Title: Discovery of Virus-Host interactions using bioinformatic tools Author: Marques-Pereira, Catarina; Pires, Manuel; Moreira, Irina S. Edited by: Shukla, AK Source: BIOMOLECULAR INTERACTIONS, PT B Book Series: Methods in Cell Biology Volume: 169 Page: 169-198 Part B DOI: 10.1016/bs.mcb.2022.02.001 Published: 2022 |